Anna Norrby-Teglund is Professor in medical microbial pathogenesis at the Karolinska Institutet, Stockholm, Sweden. She has a long standing interest in the pathogenesis of severe invasive bacterial infections, in particular infections caused by group A streptococcus and Staphylococcus aureus. She obtained her PhD degree in clinical bacteriology at Umeå University, Sweden, in 1994, after which she spent 3 years as a postdoc at University of Tennessee, Memphis. In 1997, she returned to Sweden and established her research group at the Karolinska Institutet. Her research has focused on delineating mechanisms contributing to severe manifestations of acute bacterial infections (i.e. severe sepsis/septic shock, necrotizing infections of the lung and skin) in order to identify novel targets for therapeutic intervention. The research has been translational in nature and based largely on patient materials and model systems that mimic the clinical setting. One important patient cohort is a Scandinavian cohort of patients with necrotizing soft tissue infection linked to an extensive biobank collection, which has been enrolled in an EU-collaborative project, INFECT coordinated by Norrby-Teglund. Also, we have established human 3D organotypic models of lung and skin tissue composed of both immune cells and tissue-specific cells, which allow for in-depth studies of host-microbial interactions at the tissue site of infection.
Abstracts this author is presenting: